Lymph node fine needle aspiration biopsy is a valuable technique in solving the diagnostic problems of clinically significant Lymphadenopathy. The present study was performed in the Institute Of Chest Medicine King Edward Medical College/ Mayo Hospital, Lahore during the year 2001 to evaluate the role of fine needle aspiration biopsy in the diagnosis of supraclavicular lymphadenopathy. A total of 103 patients (70 men and 33 women with mean age 42.3 years) were analyzed for their spectrum of pathology by fine needle aspiration biopsy who had significant right and left sided supraclavicular lymphadenopathy in 43 and 60 cases respectively. Fine needle aspiration biopsy showed malignancy in 19(20.6%) Tuberculosis in 57 (61.9 %) patients and nonspecific inflammation / reactive hyperplasia in 16 (17.4%) cases. The specimens were deemed inadequate for cytological analysis in 11(10.7%) of pathology which is very significant (p<.001) no significant complications occurred during and after the procedure. Our study demonstrates that fine needle aspiration biopsy is an accurate, economical and valuable tool for the evaluation of supraclavicular lymphadenopathy of various etiologies.
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