Muhammad Sehran Khalid, Sadaf Arooj, Awais Ahmed, Ali Mansoor, Mahjabeen Masood.
Diagnostic accuracy of ultrasound sonography test and computed tomography compared with magnetic resonance cholangio pancreatography in patients with obstructive jaundice considering endoscopic retrograde cholangio pancreatography as gold standard.
J Postgrad Med Inst Jan ;37(3):201-7.

Objective: To determine the diagnostic accuracy of USG and CT compared with MRCP in the patients with obstructive jaundice considering ERCP as the gold standard Methodology: This cross-sectional study at Mayo Hospital, Lahore, spanned 6 months and included 71 cases meeting predefined criteria. A senior radiologist prepared all reports. The study used preliminary ultrasound, CECT abdomen, and MRCP for patients with cholestatic jaundice, comparing results with ERCP. MRCP showed higher diagnostic accuracy. Results: MRCP proved to be the most accurate in diagnostic accuracy. Its sensitivity and specificity for benign conditions were 94.87% and 93.75% while for CT it was 87.18% and 81.25% and for USG it was 84.62% and 90.63% respectively. For malignant conditions sensitivity and specificity for MRCP was 93.75% and 97.44% for CT it was 87.5% and 92.31% and for USG it was 81.25% and 89.74% respectively. Conclusion: The results of this study demonstrate that MRCP is a superior modality, exhibiting higher sensitivity, specificity, and diagnostic accuracy for evaluating both malignant and benign conditions in patients with obstructive jaundice compared to USG and contrast-enhanced CT. MRCP's specificity for various etiologies matches that of ERCP, which is considered the gold standard. While MRCP's cost and availability may be a concern, its non-invasiveness, contrast-free nature, and high diagnostic accuracy make it an ideal choice for evaluating patients with obstructive jaundice.

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