Asia Bano, Mahwash Rana, Zareen Saqib Suleri, Muntaha Javed, Nadia Sultan, Ghazala Butt.
Comparison of efficacy and safety of topical tacrolimus vs. narrowband ultraviolet B for moderate-severe atopic eczema.
J Pak Assoc Derma Jan ;33(2):643-7.

Objective: To compare the efficacy and safety of topical tacrolimus with narrowband ultraviolet B for moderate-severe atopic eczema.   Methods: 60 subjects, equally divided into Group A and B with the former treated with topical tacrolimus and the latter received narrowband ultraviolet B (NB UVB). These patients were followed up at 2, 4, 6, 8 and 12th weeks. Efficacy and side effects of the given treatment were recorded at each visit.   Results: 90% of patients receiving NB UVB showed ≥50% SCORAD reduction as compared to 50% of cases applying tacrolimus. Fewer patients (60%) on NB UVB had side effects as compared to 66% of tacrolimus patients.   Conclusion: NB UVB is a more effective and safer therapy than topical tacrolimus in moderate-severe atopic dermatitis in our patients.  

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