Fatima Zahra, Saera Suhail Kidwai, Ayaz Ahmed, Mehrunnesa Umar, Fahad Waseem, Rukhsana Abdul Sattar.
Clinical features and short term clinical outcomes in Covid-19 infected Adult Population during fourth wave.
Isra Med J Jan ;15(1):20-4.

Objective: To evaluate the clinical characteristics and comorbidities in COVID 19 patients and analyze its impact on outcome of COVID 19 during fourth wave. Study Design: Prospective observational study. Place and Duration: Department of Medicine of Fazaia Ruth Pfau Medical College for six months i.e. from 1st June 2021 to 1st December 2021 during fourth wave of Covid 19. Methodology: The patients with confirmed nasal swab test in SARI specialized acute respiratory illness unit of hospital (report available within 12 hours) were included in the study who required admission in medical COVID ward or intensive care unit. For data collection two residents were trained and assigned to collect the data by recording history of clinical features, comorbidities. Their physical examination along with vitals, oxygen saturation, and relevant laboratory workup was carried out. They recorded all the investigations carried out in admitted patients and observed them till they got better and discharged or could not survive. Results: A total of 113 patients were enrolled, mean age of recovered patients in our study was 45.99 +- 17.80 years whereas for expired it was 71.38 +- 11.62 years (p value <0.05). In the recovered group 70.10% (68) were males and 29.90 %( 29) were females whereas expired group included 62.50% (10) males and 37.5% (6) females. Fever, cough and body aches were observed in 72.57%, 49.56% and 46.02% respectively in recovered patients and 11.50%, 9.73% and 8.85% respectively in expired patients. Diabetes mellitus, hypertension and ischemic heart disease were found as comorbidities in 5.31%, 8.85% and 2.65% of recovered patients` whereas18.75 %, 6.25% and18.75 % in expired group respectively. Conclusion: Our findings suggest that patients with COVID-19 who have presented with shortness of breath and have diabetes mellitus or ischemic heart disease are at increased risk of mortality. These patients should be closely monitored and provided with appropriate supportive care.

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