Zafar Amin, Muhammad Ilyas.
Correlation of radiological findings with histological cell types in Bronchial Carcinoma.
Pak Armed Forces Med J Jan ;54(1):88-91.

The purpose of this study is to correlate different Radiological findings of bronchial carcinoma with histological cell types using conventional radiography and CT scan (computerized tomography) and to develop sensitivity and positive predictive values for CXR (chest radiography) and CT scan findings for detecting bronchial carcinoma on basis of cell types. The study was carried out in Department of Radiology CMH Lahore. This study involved 33 consecutive patients of either sex aging between 35 - 85 years with pathologically proven bronchial carcinoma. There are four major cell types of bronchial carcinoma: adenocarcinoma, squamous cell carcinoma, undifferentiated large cell carcinoma, and small cell carcinoma. Adenocarcinoma and undifferentiated large cell carcinoma are generally peripheral lesions manifesting as solitary nodules or masses, whereas squamous cell carcinoma and small cell carcinoma are typically central and may manifest as hilar masses, atelectasis, or pneumonia. The study also showed that CXR and CT findings when combined show increased sensitivity and positive predictive values for detecting bronchial carcinoma as compared to CXR findings alone.

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