Janbaz Ahmad, Mahmood Aleem, Samina Khalid, Dawood Amin, Arif Hussain, Mehnaz Roohi, Altaf Bashir.
A profile of Gynecological Cancer: A clinicopathological anaylsis of 580 cases during 1986-1994 in Faisalabad.
Professional Med J Jan ;3(4):271-82.

The gynecological cancers have variable worldwide frequency. This is a prospective study of various types of gynecological cancers in Faisalabad, which is 3rd biggest city of Pakistan. All the cases submitted to the department of Pathology of the medical college and Principal author`s lab during the period of 1986-94 was analyzed. A total of 580 cases were documented out of which ovarian cancer was the most frequent gynecological cancer (38%) followed by carcinoma cervix (33.2%), corpus uteri (18.9%) and vulva/vagina (9.9%). The squamous cell carcinoma (SCC) was the most frequent vulval carcinoma however one case of Rhabdomyosarcoma was also observed. The SCC of the cervix was the frequent type with mean age of 45.2 years and mostly presented in grade 11. There were 73 cases of endometrial carcinoma with mean age of 40.6 years whereas Adenosquamous type and clear cell carcinoma had a mean age of 52 and 40.3 years respectively. The leiomyosarcoma was mainly of grade 11. The ovarian malignancies constituted the most frequent type (38%) of gynecological cancers and serious adenocarcinoma was (40.7%) followed by mucinous (34.8%) and endometroid (16.8%). Majority of the cases were in grade 11 and size varied from 4-28 cm. There were also 48 cases (21 %) of stromal and germ cell tumors mostly granulosa cell, dysgerminoma and malignant teratoma. This study is an initial report of gynecological cancers in this part of Pakistan, which is a developing country with alarmingly rising prevalence of carcinomas. Malignancies are now one of the leading causes of morbidity and mortality in the population.

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