Tayyaba Batool, Jamshed Akhtar, Soofia Ahmed, Farhat Mirza, Shazia Jalil, Aqil Soomro, Nasir Saleem, Yaqoot Jehan, I Shaikh M Ali, Raees Taqvi.
Antibiotic sensitivity pattern in burn wound cultures.
J Surg Pak Jan ;10(1):8-11.

Objective: To find out the pattern of microbial flora and their sensitivity to antibiotics in burn wounds cultures. Design: Descriptive study. Place & Duration During year 2003, at Burns unit, National Institute of Child Health, Karachi. Subject And Methods: Twenty five consecutive patients were included in the study and pattern of most common pathogens was studied with special reference to their antibiotic sensitivity. The bacterial cultures were taken at different intervals during the hospital stay, first on the second day of admission and then subsequently, following every 7-10 days. Antibiotic sensitivity pattern was correlated to the antibiotic the patients were receiving. Results: Our results revealed that the most frequent isolate was pseudomonas (80%) followed by staphylococcus aureus (40%), klebsiella (28%), proteus (16%) and streptococcus (8%). Time related changes showed that the bacterial isolates were predominantly gram negative rods (70%). in the first culture taken on the 2nd day of admission and remained high throughout the hospital stay and was up to 90% in the final culture. Conclusion: There is a specific pattern of burn wound microbial colonization, with time related changes in dominant flora. Antibiotic sensitivity profile is helpful to make guidelines for dealing with the burn wound at the outset and for which antibiotic to start with. Following this protocol the morbidity and the resistant flora could be avoided.

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