Muhammad Alam, Asm Akhtar, Syed Jamal Raza.
Association of maternal glycemia with neonatal complications.
J Surg Pak Jan ;10(3):31-3.

Objective: To find out the relation of maternal glycosylated haemoglobin (HbA1c), maternal weight at first antenatal visit and weight gain during pregnancy with birth weight of the baby. Patients and Method: Sixty infants of diabetic mothers were enrolled over period of six months. The 3rd trimester glycosylated haemoglobin of the diabetic mothers was done at term or post term. The neonates were evaluated for macrosomia and screened for hypoglycemia, hypocalcemia, hyperbilirubinemia, birth asphyxia, birth trauma and congenital anomalies. Linear correlation analysis for bivariate data was performed to study the relationship between maternal HbA1c and birth weight. Correlation coefficient was also calculated for various maternal variables (weight at 1st antenatal visit and maternal weight gain) and birth weight. Results: Twenty seven (45%) IDMs out of 60 were macrosomic. Correlation coefficient for HbA1c and birth weight was 0.44. This showed a mild linear relation of the two variables. Maternal weight at fast antenatal visit showed an even weaker correlation with birth weight (r=0.24). Conclusion: Maternal HbAlc level should be used to monitor the maternal glycemic control and thereby reduce the chances of macrosomia.

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