Saify Z S, Ozra Ahsan, Abdullahdayo.
Cineole as skin penetration enhancer.
Pak J Pharm Sci Jan ;13(1):29-32.

Cineole is a chief constituent of eucalyptus oil and constitutes almost 80% of this essential oil. A study was conducted on skin penetration enhancing capacity of cineole (I, 8-cineole) towards the permeation of 5 flurouracil in excised rat skin; it caused almost 83 fold increase in drug pemeability co-efficient, the mode of action of acceleration may be described by combined process of partition and diffusion.

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