Saify Z S, Faiyaz H M Vaid.
Synthesis and anti-microbial screening of some Piperidine derivatives.
Pak J Pharm Sci Jan ;11(1):15-21.

Synthesis of piperidine derivatives viz, l-(4`-methoxy phenacyl)- N-Methyl piperidinium bromide, and 1-(4`- nitrophenacyl)-N-methyl piperidinium bromide, and l-(3`, 4`-dihydroxy phenacyl)-N-methyl piperidinium chloride was carried out by quarternizing N-methyl piperidine with corresponding phenacyl halides. The structures of these compounds were elucidated by spectroscopic techniques such as UV, IR, El mass and 1H-NMR. The compounds were subjected to antimicrobial screening in quantities of 10 mg/ml dissolved in DMSO. Disc diffusion method was used to observe the significance of these compounds against seven bacterial and one fungal cultures.

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