Kalantan R, Alotaibi Gh, Salwa Khier.
An in vitro investigation of the Cytotoxicity of recent gingival retraction materials.
J Pak Dent Assoc Jan ;14(3):145-9.

OBJECTIVE: This study was conducted to determine the cytotoxicity of some recently introduced tissue retraction materials and to compare their cytotoxic effects on the human gingival tissue. MATERIALS AND METHODS: One representative brand of the commonly used conventional tissue retraction materials (Gingi-pak) along with two recent types (Expasyl and SnoWhite as a part of PerfectlM systems) were used in this project. A total of 27 specimens were prepared and divided into three groups, nine of each tested material. The cytotoxicty of the tested specimens was judged using the cell viability method along with direct contact test in an especially prepared culture at different time periods. RESULTS: The obtained results showed qualitatively that Gingi-pak material did inhibit the cell growth of the used culture media . On the other hand, Expasyl and SnoWhite (as a part of PerfectlM Systems) materials produced very slight growth inhibition of the cultured cells with some observed detached cell linings. CONCLUSIONS: The conventional gingival retraction cord impregnated with adrenaline; Gingi-pak was the most toxic material among the tested materials at all time periods.

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