Wael Hayel Khreisat.
Clinical profile of epilepsy during the first two years of Life.
Pak J Med Sci Jan ;22(1):55-9.
Objective: This study aims at identifying the different presentations of infantile epilepsy with their E.E.G. and neuro-radiological patterns. Patient & Methods: Patients included in this study were children suffering from epilepsy starting below 2 years of age. They were attending the outpatient clinic or were from the in-patient departments in Prince Ali – Ben Al - Hussein hospital. The study included 100 children with ages ranging from three month to two years. All patients were subjected to: careful history taking, general and neurological examination including fundus examination, E.E.G. tracing, CT were done for all cases. Febrile convulsions and convulsions due to metabolic disturbances were excluded from the study. Results: Patients were divided clinically into 2 groups: Group A (symptomatic) group-80 cases (80%): included those who had evident etiology, evident neurological deficit or developmental delay of significant degree prior to onset of seizures while Group B (cryptogenic) group-20 cases (20%). male to female ratio was 1.5: 1. The etiological factors encountered were perinatal asphyxia (55%) while heredofamilial disorders were least common 44% of patients had normal clinical examination as well as development while 27 % were mentally handicapped. The generalized tonic-clonic seizure was the commonest in both group while infantile type was the least, EEG was normal in 18 % of cases while CT scan lesion were present in 70% of the patients. Conclusions: Careful history taking is extremely important for accurate diagnosis of epilepsy. The investigation of choice is the E.E.G. Computerized tomography should be considered an accurate neurodiagnostic test. It provides a good anatomic description of the brain.
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