Muhammad Shoaib Khan, Afzal Saeed Awan, Muhammad Vaseem, Zaka Ullah Malik, Muhammad Aamir Mian.
Perforated duodenal ulcer.
Professional Med J Jan ;12(4):379-85.

Objective: Perforated duodenal ulcer is a common surgical emergency. Controversy exists regarding simple closure of perforation or definitive surgery in emergency setting. The objective of the study is to see the result of simple closure of perforated duodenal ulcer followed by eradication of H. Pylori in young soldiers. Design: Descriptive and analytical. Place and duration of study: This study was carried out at CMH Kharian/CMH Rawalpindi between Jan 1998 to June 2002. Subject and method: Fifty three young soldiers presenting with perforated duodenal ulcer were included in the study. They were treated with simple closure of perforation followed by eradication of H. Pylori. These patients were followed up in OPD for two years. Depending upon their symptoms they were placed in different Visick grades. Result: Six patients (11.3%) were lost in followup and excluded from the study. Out of remaining forty seven patients thirty nine patients (82.5%) remained asymptomatic and did not require further treatment. Four patients (8.5%) required symptomatic treatment. Three patients (6.3%) required another course of omeprazole. One of them (2.1%) required vagotomy and gastrojejunostomy for gastric outlet obstruction. Conclusion: It was concluded that simple closure of perforation with H. Pylori eradication is a simple and safe procedure to treat this emergency.

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