Ishtiaq Ahmed Malik, Khalid Mahmood, Khalid Raja.
Acute myocardial infarction.
Professional Med J Jan ;12(4):457-65.

Acute myocardial infarction is still one of the major killers of mankind. Minute means muscle i.e., earlier the management is started in the form of thrombolytic therapy, better is the prognosis. For this purpose, researchers all over the world are striving hard to find the tests, which can be used in making the early diagnosis. Rapid Troponin-T test is a new addition to the battery of tests. Design: A prospective study. Setting: In Armed Forces Institute of Cardiology. Period: From Jan 2004 to Jan 2005. Objectives: To study the comparative efficacy of rapid Trop-T test verses conventional biomedical markers like creatine kinase MB (CK-MB) and Lactic Dehydrogenase (LDH). Material & Methods: Fifty patients of both sexes and all age groups fulfilling WHO criteria of new onset acute myocardial infarction were included in the study. Rapid Trop-T test, CK-MB and LDH were performed on every patient at 0,2,4,6,12 and 24 hours on day one, and daily from 2 to 7 days. Rapid Trop-T assay had almost same sensitivity and specificity as CK-MB in early hours after infarction and LDH in the next few days after infarction, this test has few clear advantages of being easy to perform, requiring no special equipment and expertise, and can be useful tests at peripheral hospitals lacking good laboratory setup.

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