Nasir Mehmood, Nadeem Rizvi, Rashid Ahmed Khan, Riaz Hussain Shah.
Role of Computed Tomography-Guided Percutaneous Transthoracic Needle Lung Biopsy in the Diagnosis of Peripheral Pulmonary Mass Lesion.
J Coll Physicians Surg Pak Jan ;11(8):482-5.

Objective: To evaluate the diagnostic yield and complications of computed tomography (CT)-guided percutaneous transthoracic needle lung biopsy (PTNLB) of peripheral pulmonary mass lesion. Design: This is a retrospective study. Place and Duration of Study: It was conducted in the Department of Chest Medicine, Jinnah Postgraduate Medical Centre, Karachi over a period of two years from January, 1997 to December, 1998. Subjects and Methods: We retrospectively reviewed 41 case records of patients who underwent CT-guided percutaneous transthoracic lung biopsy during January, 1997 to December, 1998 having radiological evidence of peripheral pulmonary mass lesion. A special proforma was designed to record demographic data, clinical features, biopsy results and complications of the procedure. Subsequently results were analyzed. Results: Adequate tissue specimens were obtained in 37 patients out of a total of 41, the tissue pickup rate was 90%. In all 37 patients specific histological diagnosis was made, 32 (94%) had primary malignant lesions, 02 (6%) metastatic malignant lesions and 03 (8%) benign lesions. No complications were observed except mild pain at the site of procedure. Conclusion: CT-guided PTNLB is a safe and effective procedure in obtaining specimens for pathological diagnosis of peripheral pulmonary mass lesion.

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