Hend Alnahedh.
Clinical evaluation of the efficacy of Carisolv chemo-mechanical caries removal.
J Pak Dent Assoc Jan ;15(1):22-7.

OBJECTIVE: The aim of this study was to evaluate the caries-dissolving efficacy of Carisolv (Mediteam, Gothenburg, Sweden) gel in vivo. Treatment time, perception of pain and discomfort and the use of local anesthesia were also evaluated. PATIENTS AND METHODS: 56 patients that have at least two large carious lesions not involving the pulp and no history of spontaneous pain were selected. All patients were randomized for both chemo-mechanical and drilling treatment and a questionnaire regarding treatment progress and patient`s experiences was filled out for each case. RESULTS: Measurements of treatment time showed that the gel took a significantly longer time to remove caries than drilling, 8.43 minutes and 7.14 minutes, respectively. On the other hand, Carisolv caused less pain and discomfort than drilling, only 8 of the gel group patients demanded anesthesia, while 20 of the drilling group did. Furthermore, 30 patients of the gel group and 5 of the drilling group did not feel any pain. Carisolv did not completely eliminate the need for drilling, in 89.3% of cases minor modification of the preparation was done using rotary instruments. CONCLUSION: The results show that Carisolv is an effective method for caries removal. It is slower than conventional cavity preparation, however, it reduces the need for local anesthesia and patients seem to prefer it.

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