Arshad Mahmood Malik, Zahoor Ahmed, Ulfat Bashir.
Immediate tissue response comparison of wound after partial Glossectomy by 3 watt, 6 watt CO2 laser and scalpel.
Ann Pak Inst Med Sci Jan ;1(4):220-6.

Objective: To compare advantages and disadvantages of COs laser and scalpel after an oral surgical procedure. Place and Duration of Study: This study was carried out at animal laboratory of Post Graduate Medical Institute, Lahore about three months. Subjects and Methods: This study was conducted on 30 Sprague - dawley Albino rats, which were divided into 3 equal groups of 10. Partial glossectomy was done with 3 watts COs laser for first group (A), with 6 watts COs laser for second group (B) and with scalpel for third group (C). Wound healing was observed and compared grossly and histologically, immediately after surgery. Results: Significant differences were seen in gross wound appearance in A and B groups as compared to C group. Histological formation of zones, thickness of blood and carbonization were highly significant in A and B groups compared to group C. Conclusion: CO2 laser wound was much better compared to scalpel in terms of bleeding duration, surgery duration, and wound appearance and in surface coverings.

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