Mathew Ebose Enosolease, Augustina Omolade Awodu.
Proptosis and blindness: an unusual primary presentation of chronic granulocytic Leukemia.
Pak J Med Sci Jan ;22(3):326-8.

Proptosis and blindness are uncommon presentations of chronic granulocytic leukaemia. We present a 20-year old man with four months history of bilateral swelling of the eyes and deteriorating vision, abdominal swelling and early satiety. Examination revealed massive splenomegaly and bilateral blindness resulting from retinal detachment most probably due to retro-orbital accumulation of malignant myeloid cells. Peripheral blood film confirmed chronic granulocytic leukaemia, CGL. Clinical response to hydroxyurea was excellent but retinal detachment and blindness persisted. We suggest that CGL should be excluded in all cases of painless eye- swelling.

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