Humaira Akram, Alia Nasir, Tabinda Rana.
Increasing severity of Polyhydramnios - a risk factor for congenital malformation.
Biomedica Jan ;22(1):5-11.

This study was carried out to know the frequency of fetal anomalies in pregnancy complicated by polyhydramnios. The place of this work was Obstetrics & Gynaecology, Unit-III Lady Willingdon Hospital, Lahore. The study period was from 1st May to 31st Dec. 2005. Sixty consecutive patients with polyhydramnios were included in the study. Amniotic fluid volume was calculated by measuring amniotic fluid index (AFI) through ultrasound and type of fetal anomaly was also diagnosed on ultrasonography. Our results depicted that there were 22(61.2%) normal fetuses with mild polyhydramnios (AFI 24 to 29.9cm) whereas in severe polyhydramnios (AFI 35 cm or more) all fetuses (100%) had congenital malformations. It was thus concluded from this study that increasing severity of polyhydramnios is associated with increasing frequency of fetal anomalies.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com