Fawad Alam, Wasima Talat, Aneel Aslam, Adeel Aslam.
Apgar score of Neonate; comparison of thiopentone and propofol during C-section..
Professional Med J Jan ;13(2):175-7.

A comparative study was conducted in CMH, Malir, CMH, Kharian and WT (Pvt) Ltd. Gynaecology and Obstetrics, Multan from April 2001 to March 2004. The Apgar score of neonate was compared for thiopentone or propofol in C-section patients. Two groups of patients were made. Group-A was induced with thiopentone and group-B was induced with propofol. Each group had 100 patients. In group-A 13 neonates required manipulation and 2 neonates in group-B also required manipulation like mask ventilation or endotracheal intubation and one of drugs like atropine to improve apgar score. 13% neonates in group-A and 1% neonates in group-B required manipulation. This clearly shows the superiority of propofol over thiopentone as an induction agent in C-section. The P value of group-A was 0.13 and for group B was 0.02 and had had a statistically significant difference.

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