Objective: To investigate the course of intraocular pressure after cataract surgery in patients having pseudo exfoliation syndrome but without any evidence of glaucoma. Design: Prospective age-matched comparative type. Place and Duration of Study: Department of Ophthalmology, Combined Military Hospital, Peshawar and Military Hospital, Rawalpindi. From 1st November 2003 to 30th April 2004. Patients and Methods: Ninety five patients having cataract, were divided into two groups. Group I consisted of forty five patients with pseudo exfoliation syndrome and Group II comprised control group of fifty patients not having pseudo exfoliation. All the patients underwent extra-capsular cataract extraction with posterior chamber intraocular lens implantation. The intra- ocular pressure was measured pre-operatively as well as on 7th post-operative day, 1st and 3rd post-operative months, in addition to other pre- and post-operative evaluation. Results: Statistically, there was no significant difference in the pre-opera tive intraocular pressure between the two study groups. At 7th post-operative day, the intraocular pressure was below 18 mm of Hg in all the patients. First and 3rd month after the surgery, a decrease in intraocular pressure was observed. The inter-group differences in intraocular pressures at 1st and 3rd post-operative months were statistically not significant. Conclusion: Seven days after extra-capsular cataract extraction with posterior chamber intraocular lens implantation, no increase in intraocular pressure was observed in the eyes with pseudo exfoliation syndrome. Three months after cataract surgery, intraocular pressure levels decreased in eyes with pseudo exfoliation syndrome similarly as in control group.
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