Rukhshan Khurshid, Mubasshir A Sheikh, Farida Munnawer.
Geographical / Physiological Diversity of Female Breast Cancer among Developing and Developed Countries.
Pak J Med Sci Jan ;17(2):99-105.

Object: To find out geographical/Physiological diversity of female breast cancer among developing and developed countries. Design: Prospective observational study. Setting: Cancer Ward and out-patient of Radiotherapy Department, Jinnah Post Graduate Medical Centre, Karachi, Pakistan. Patients: 100 female patients with histologically verified breast cancer. Results: Majority of the patients in this study were middle class housewives. Thirty women were addicted to beetle nuts. None of the patients had family history of breast cancer. Fifty-one developed cancer in right breast and forty-nine in the left breast and it was seen common in 4th and 5th decade. 70% hod Intra ductal carcinoma and 27% had invasive ductal carcinoma. 25 patients had breast cancer since three years while 72 had it for the last four five months. ESR status was positive in 70 patients and negative in 30 patients. Conclusion: Seventy-five percent of breast cancer occurs in Pakistani women with no recognized major risk factor. Further research is needed on the population of different cities of Pakistan to find the actual risk factor responsible for the disease.

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