Muhammad Khalid Masood, Itaat Ullah Khan Afridi, Muhammad Rizwan, Muhammad Yaqoob, Tahira S Izhar, Abdul Waheed Qureshi.
Complications and immediate clinical outcome of exchange transfusion in Neonatal hyperbilirubinemia.
Pak Paed J Jan ;29(1):3-8.

Objectives: To find out the complications and immediate clinical outcome of exchange transfusion for neonatal hyperbilirubinemia during hospital stay. Design: Prospective descriptive study. Place and duration of study: This study was conducted at The Children`s Hospital & The Institute of Child Health, Lahore, from September 2001 to August 2002. Patients and method: A total of 50 jaundice neonates with indirect hyperbilirubinemia (25mg/dl to 30mg/dl) underwent exchange transfusion according to Kleigmen and Behrman criteria. Results: Age of the babies ranging from 0-28 days. There were 34 male and 16 females babies. Hemolysis was the most common cause of hyperbilirubinemia. ABO incompatibility was noted in 20 babies, Rh incompatibility in 4 and both in 3 cases. G-6PD deficiency was noticed in 2, cephalhematoma in 3 babies. Cause could not be ascertained in rest of the 18 babies. Complications noted during exchange transfusion were bradycardia, acidosis, hypocalcaemia etc. mortality rate was 4%. Conclusion: Haemolysis was the most common cause of hyperbilirubinemia in babies under going exchange transfusion. Exchange transfusion for unconjugated neonatal hyperbilirubinemia was a fairly safe procedure with minimal complications.

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