Mohammed Omar Galal, Amin Muhammed Arfi, Jameel Alata, Arif Hussain, Amjad Kouatli.
Alpha2 - blocker helps to avoid systemic to pulmonary shunt in a prostaglandin dependent infant with critical pulmonary valve stenosis.
J Coll Physicians Surg Pak Jan ;16(12):780-2.

A 27 days old newborn with critical pulmonary valve stenosis remained prostaglandin (PGE1) dependent for 2 weeks after successful balloon valvuloplasty. Only the introduction of Phentolamine in his medication regimen, allowed PGE1 to be weaned off within days of this therapy. The medication was continued for 4 days and replaced by angiotensin converting enzyme inhibitor (Captopril). Few weeks after the discharge, the patient remained clinically stable with acceptable saturation.

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