Ayesha Shaukat, Farid Zafar, Muhammad Aslam, Aftab A Choudhri.
Chronic anal fissure; role of chemical Sphincterotomy.
Professional Med J Jan ;13(3):354-7.

Objective: To evaluate the role of chemical sphincterotomy in the treatment of chronic anal fissure. To compare the effects of xylocaine gelly 5% with GTN 0.2%. Design: Comparative study. Setting: Outdoor and Emergency Department of Surgical unit II and III of Sir Ganga Ram Hospital Lahore Period During the year 2004 Methods and materials: 40 patients of chronic anal fissure were included in study and was divided in a randomized manner into two groups and the effects, out come and side effects of the Xylocaine 5% and GTN 0.2% were noted, while treating the patients of chronic anal fissure. Results: At 4 weeks only 2 patients of Group A (xylocaine 5%) showed healing evidence while 8 patients of Group B (GTN 0.2%) had shown the healing of the anal fissure. At the end of the 6 weeks a total of 4 patients of Group A showed healing while in case of Group B 14 patients had shown the healing of the anal fissure. Conclusion: Our study suggests that topical GTN produces successful chemical sphincterotomy. It not only helps in relieving pain but also promotes healing of fissure. Lignocaine may help in relieving pain but it is not effective in healing of fissure.

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