Ghazanfar Ali Sirhindi, Syed Shahid All.
Effect of smoking on erythrocyte sedimentation rate (ESR) and lipid profile in adults.
Pak J Med Health Sci Jul ;1(1):33-4.

Objectives: The study was designed to find out changes in ESR and serum lipid profile in adult smokers and non-smokers and risk of development of atherosclerosis. Study Design: It is a comparative and non-interventional study. Study Period: 1st October to 31st October, 2005 Setting: Study was carried out in Department of Pathology, Punjab Postgraduate Medical Institute, Lahore. Subjects and Methods: A total of 100 males of adult age (18-65 years) were selected, out of which 50 were smokers and 50 were non-smokers. ESR was done by modified Westergren method and lipid profile was done by chemistry analyzer (Microlab 300 MERCK). Results: A significant increase in ESR, serum total cholesterol (TC), low density lipoprotein cholesterol (LDL-c) and mean serum triglyceride (TG) levels were observed in smokers as compared with nonsmokers. While levels of serum high density lipoprotein cholesterol (HDL-c) were significantly lower in smokers as compared with non-smokers. Conclusion: Smoking produces adverse effect on lipid profile and ESR thus enhancing the risk of atherosclerosis.

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