Muhammad Muzaffar, Naheed Ghani, Samina Iltaf, Saleha Moghal, Ayesha Nayyar, Fouzia Rana.
Invasive squamous cell carcinoma of the conjunctiva.
Pak Armed Forces Med J Jan ;57(4):344-5.

A male patient aged 55 years presented to us with history of recurrent swelling in the conjunctiva, irritation and redness of eye. The patient was HIV negative. There was also history of removal of a cyst in limbal area three months back. When granulation tissue along with previous scar was biopsied it showed a well differentiated squamous cell carcinoma arranged in sheets and groups with thin intervening fibrovascular septa (fig. 1). There was moderate degree of pleomorphism. Tumour cells showed high N/C ratio and frequent mitoses. Nuclei of the cells were hyperchromatic to vesicular with prominent nucleoli. There were foci of individual cell keratinization (fig. 2). There was evidence of vascular invasion at some places. Wide excision was done and mitomycin C therapy started.

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