Jawad Jalil, Nasser Rashid Dar, Mobeen Shafique.
Rosai Dorfman disease- a rare entity report of two cases with nodal and extranodal involvement.
J Pak Med Assoc Jan ;58(6):338-40.

Rosai Dorfman Disease (RDD) also known as Sinus Histiocytosis with Massive Lymphadenopathy (SHML) is a very rare variety of reactive histiocytoses. It commonly involves cervical lymph nodes, although involvement of other lymph node regions, skin and other organ involvement can occur. It has a good prognosis so there is a need to differentiate it from other lympho proliferative disorders of poorer prognosis. We present two cases of this rare disorder illustrating its clinical spectrum; a 22 years old woman with involvement of submandibular lymph nodes, nasal septum and sub-glottic region and a 45 years old male with prominent skin involvement.

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