Nasreen Laiq, Mohammad Naeem Khan, Shahid Khan, Akbar Said Jan.
Induction and emergence characteristics of Propofol and Halothane versus Sevoflurane in day case eye surgery in Children.
J Postgrad Med Inst Jan ;22(1):57-61.

Objective: To compare the induction and emergence characteristics of Propofol and halothane with sevoflurane in day case Eye surgery in children. Material and Methods: 100 patients undergoing day case eye surgery were randomised to two groups of fifty patients each. Group A received combination of I.V propofol 1% (induction) and halothane/nitrous oxide (maintenance) while group B received sevoflurane/nitrous oxide alone. Patients demographics, age, sex, ASA status, duration of surgery and time required for anaesthetic induction, maintenance and time to discharge home were recorded for both groups. Postoperative nausea, vomiting (PONV) and incidence of adverse events during induction and recovery were also noted. Results: The mean age was 7.3+2.36 years in group A and 7.4+1.54 years in group B. ASA status, male female ratio, duration of surgery, and the need for intraoperative analgesics between two groups were similar. There were no significant differences in the incidence of laryngospasm, breath holding or coughing between groups. In postoperative recovery room there was no significant difference regarding nausea and single emetic episode in both groups. While postoperatively in the ward, the incidence of nausea and single emetic episode was noted in 6(12%) and 3(6%) patients respectively in group B as compared to 2(4%) patients and 1(2%) patients in groups A (P <0.05). Conclusion: The incidence of adverse events during induction and PONV in the sevoflurane group suggests that sevoflurane is not ideal as a sole anaesthetic agent in pediatric day case anaesthesia.

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