Abdul Salam Kalhoro, Saifullah Jamro, Amanullah Abbasi, Sikandar Ali Mughal.
A study of posterior urethral valves.
J Surg Pak Jan ;13(3):112-6.

Objective: To determine the clinical manifestations of posterior urethral valves (PUV) and outcome of early diagnosis and management. Study Design: Descriptive study Place and duration of study: Department of Paedaitric Surgery, Paediatric Medicine and Urology at Chandka Medical Hospital Larkana, from January 2002 to December 2006. Patients and Methods: All the patients of paeditric age group having urinary complaints with suspicion of PUV were included in this study. Diagnosis was based on ultrasonography of urinary tract and voiding cystourethrography (VCUG). Results: Fifty one male children with PUV on VCUG were enrolled into the study. Two patients were suspected on antenatal ultrasound of having bladder outlet obstruction. Most of the patients presented after 3 years (40%) and 15% presented at 9 years of age. Common clinical presentations were fever, anaemia, failure to thrive and urinary symptoms. Around 53% had abnormal renal function, 40% had vesico ureteric reflux (VUR). Nearly all patients presenting after 6 years of age had abnormal renal functions and VUR. Early surgical intervention had better resolution effect. Conclusions: PUV is common cause of the lower urinary tract obstruction in male children. Delay in diagnosis and treatment leads to end stage renal disease.

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