Morteza Javaid, Shabahang Mohammadi, Saleh Mohebbi.
Management of Invasive Fungal Sinusitis.
Pak J Otolaryngol Jan ;24(3):38-9.

Invasive fungal sinusitis (IFS) caused commonly by Mucoraccae. Mucormycosis is usually occurs in patients with immunodeficiency. It has high mortality rate. OBJECTIVE: Since there has not been a clear protocol for treating these patients and, we decided to establish a protocol for IFS management. STUDY DESIGN: Retrospective and descriptive study. PATIENTS & METHODS: This study included 30 patients who were suspected of having IFS. After confirming the pathogen, medical staff selected the proper protocol for treatment. RESULTS: The site involvement included nose and orbital cavity (53.3%), brain in conjunction with sinonsal (36.6%) and simple nasal cavity involvement (10%). 86.6% of the patients had underlying diseases. Diabetes as single underlying disease in 56.6% while both diabetes and renal failure were found combined in 13.3%. Acute lymphocytic leukaemia in 6.65%, 3.3% renal failure, lupus 3.3% and 3.3% chronic lymphocytic leukemia etc. Mortality was 40%. We categorize the patient in 3 groups: only sinonasal, sinonasal and orbit, and associated brain involvement which have very poor prognosis.

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