Abed El Hakeem Noman El Jadba, Mansour Sobhi El Yazji.
Neonatal Septicemia in Gaza City Hospitals.
Pak J Med Sci Jan ;25(2):226-31.

Objective: To determine the most common pathogens and antimicrobial sensitivity of neonatal septicemia in Neonatal Intensive Care Units (NICU) in Gaza City hospitals. Methodology: This prospective descriptive study was carried out in (NICU) in Al-Nasser and Al- Shifa hospitals in Gaza City, between January 2004 to January 2005. The patients were categorized into two groups of early and late onset septicemia. Results: Three hundred twenty eight neonates out of 2487 cases had positive blood cultures with infection rate of 13.2%. The most common isolated pathogens were Coagulase negative Staphylococci, E. coli, and Klebsiella spp. These isolates were most sensitive to meropenem, amikacin, vancomycin, chloramphenicol, ciprofloxacine and third generation cephalosporine. The highest percentages of isolated pathogens were obtained from Al- Nasser hospital with infection rate of 52.9% for early onset sepsis and 84.5% for late respectively. While in Al-Shifa hospital the rate of early onset sepsis was 47.1% and 15.5% for late onset sepsis respectively. Conclusion: There is a difference between the types of septicemia found in two hospitals (early onset and lately onset septicemia) with a prevalence of Coagulase negative staphylococci (57.3%), E. coli (10.4%), Klebsiella spp. (8.0%) and others (24.3%). The most effective antibiotic for Gram negative isolates was meropenem, while the most effective antibiotic for Gram positive isolates was vancomycin.

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