Robina Firdous.
Abdominal surgery.
Professional Med J Jan ;12(3):340-5.

The severity of post-operative pain and the lack of efforts in relieving it have led to the involvement of Anaesthesiologists in the management of post-operative and acute pain. Parenteral opiates have been utilized for post-operative pain management. The identification of the opioid receptors on substantia gelatinosa has provided an alternate route i.e the epidural route for administering opiates. Objectives: To evaluate 1 and compare the efficacy and side effects of parenteral Buprenorphine with those of Extradural Buprenorphine. Setting: Department of Anaesthesia, District Headquarter Hospital, Faisalabad. Period: The data was collected during the last three and a half years. Materials and Methods: Sixty adult patients of either sex and ages ranging from 35-45 years, who underwent lower abdominal surgery, were randomly selected for the study. They were equally divided into two groups. Group I patients were administered Buprenorphine 0.3 mg through the epidural catheter in extradural space. Group II patients were given Buprenorphine 0.3 mg intramuscularly. Results: Buprenorphine through the epidural route gives better analgesia with fewer side effects as compared with the parenteral route.

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