Khadija Bano, Talat, Samreen Iqbal.
Alternative to surgical evacuation of uterus: Misoprostol for post-abortion care.
J Surg Pak Jan ;14(2):53-7.

Objective To compares the effectiveness of single 600 micrograms (µg) dose of sublingual misoprostol with manual vacuum aspiration (MVA) for treatment of incomplete and missed abortions. Study design Quasi- Experimental study. Place & Duration of study. Post-abortion care room, Jinnah Postgraduate medical centre (JPMC) Karachi, from September 2008 to December 2008. Patients and Methods Hundred consenting women with incomplete and missed abortions were randomized to either a single dose of 600 micrograms of sublingual misoprostol or MVA for treatment of their condition. Main outcome measure was complete abortion following initial treatment. Secondary outcome measures were satisfaction rate and acceptability of the method. Results Regardless of treatment assigned, nearly all participants had a complete uterine evacuation (Misoprostol =92 % MVA= 100% p = 0.12). A slightly more satisfaction rate was observed in the misoprostol group (p=0.001) as 86% participants expressed desire to choose misoprostol again while the number was 76% in MVA group. Conclusions Sublingual misoprostol is as safe and as effective as manual vacuum aspiration for post-abortion care.

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