Ijaz Mohammad Khan, Mohammad Javed, Muhammad Kamran Hassan, Shabir Ahmad Khan, Sher Rehman.
Clinical profile of ulcerative colitis.
J Med Sci Jan ;18(1):67-70.

Objectives: To study the clinical profile of ulcerative colitis (UC) in patients admitted to a tertiary care hospital in Peshawar. Material and Methods: The study was conducted in the Department of Gastroenterology and Hepatology, Postgraduate Medical Institute Hayatabad Medical Complex, Peshawar, from January 2007 to December 2008. A total of hundred patients of previously established as well as newly diagnosed cases of ulcerative colitis were included in the study. A detailed history was taken and a thorough physical examination was performed on every patient. All patients were investigated with flexible sigmoidoscopy/ Colonoscopy and findings were recorded on a standard proforma. The results were analyzed using SPSS version 10. Results: Out of 100 patients studied, 64 (64%) were male and 36 (36%) were female. The majority (56%) of patients were between 10 -30 years of age.The age range was 5 -70 years. The mean age was 26.08 years. Eighty percent of the patients were from Northern areas and 16% from Southern areas of NWFP. Ninety percent of patients presented with intestinal symptoms like bloody diarrhoea and abdominal pain. Clinically 56% of the patients had severe disease, 24% moderate disease and 20% had mild disease. On colonoscopy 12% of the patients had proctosigmoiditis, 56% left sided colitis and 32% had pancolitis. Twenty six percent of patients presented with extra intestinal manifestations. Conclusion: Ulcerative colitis is more common in young males, most of them present with severe disease and extraintestinal manifestations are not very rare.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com