Samina Shamim, Nadeem Chohan, Sobia Qmar.
Pattern of congenital malformations and their neonatal outcome.
J Surg Pak Jan ;15(1):34-7.

Objective: To determine the pattern of major congenital malformations in neonates admitted in a tertiary care NICU and evaluate their early outcome. Study design: Descriptive study. Place & Duration of study Department of Pediatrics, Liaquat National Hospital & Medical College Karachi, from January to December 2009. Methodology: A total of 431 neonates were admitted in NICU including those referred from outside. Children with major congenital malformations were identified by clinical examination and confirmed by appropriate radiodiagnostic methods. These neonates were immediately referred to the surgical team for intervention. Results: A total of 57 neonates were admitted during the study period. Thirty one were males and 26 females. Fetal anomalies were diagnosed correctly in 17 cases out of a total of 19 inborn deliveries on maternal ultrasound while it was missed in one fetus and incorrectly diagnosed in one case. A total of 48 patients had surgery out of which 4 (8.3%) died in the neonatal period. Five cases were booked for elective surgery beyond the neonatal period. Out of 4 neonates with congenital heart disease one case was referred outside, one neonate died preoperatively while 2 infants were managed conservatively. Conclusions: Due to detection of fetal anomalies, early surgical intervention, and intensive neonatal care, most infants can be rescued after a successful primary operation.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com