Tariq Zahid Khan, Atif Hafiz, Zeba Ahmad, Salman Mati Ullah, Muhammad Saleem Marfani.
Analysis of causative factors in oral cancer.
J Dow Uni Health Sci Jan ;3(3):108-3.

Objective: To analyse different causative factors leading to oral cancer. Study Design: Descriptive type of study. Setting: This study was conducted at the department of E.N.T, DUHS, Karachi. Study Period: From Jan 2008, to October 2008. Subjects & Methods: Fifty histopathologically proven patients of oral cancer were selected and analyzed regarding predisposing and causative factors. Patients having premalignant oral disease, post operative, post radiotherapy patients and patients with inconclusive reports of histopathology were not included in this study. Results: The analyses of 50 cases of oral cancer revealed that the majority of the patients were indulged in the habit of Paan, Betel nut, Naswar, Tobacco Chewing and smoking. 42 out of 50 patients (84%) had history of indulgence into these habits. Only eight out of 50 cases (16%) had no habit of Pan, Betel nut, Naswar and smoking. Early tertiary care hospital presentation was only 36% and patients presented with stage II or I. Sixty four percent (64%) patients who reported at Civil Hospital Karachi (CHK) had stage III or IV. Conclusion:The analysis of fifty patients of oral cancer revealed that majority of the patients were indulged in different chewing and smoking habits. Betel nut, Tobacco, Naswar and Paan Chewing were different causative and predisposing factors of oral cancer.

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