Sadiqa Syed, Masood A Qureshi.
Fibronogen titer and Glycemic status in women using Contraceptives.
J Coll Physicians Surg Pak Jan ;12(1):16-22.

Objective: To assess the coagulation and glycemic status in Pakistani women using contraceptives. Design : The study was conducted prospectively on 70 women and compared with 10 age-matched controls. Place and Duration of Study: The study was conducted at Karachi. Period of study was 18 month. Subjects and Methods: Eighty women aged between 20-45 years selected from low socioeconomic class and poor family background were categorized in control (n=10) and oral and injectable contraceptive users (n=70). The contraceptives used were tablet Lofemenal, injection Norigest and Norplant implant. Their blood was tested for fibrinogen titer and random blood glucose. Results: There was no appreciable difference either in fibrinogen titer or plasma glucose levels in injectable users as compared to controls, but increased incidence of high fibrinogen titer and borderline blood glucose was observed in oral contraceptive users 25% and 20% respectively. Conclusion: It was concluded that long-term use of oral contraceptives (> 3 years) might increase the thrombotic tendency and elevate the plasma glucose levels especially in women above 30 years of age.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com