Yaseen Khan, Niaz Muhammad, Arif Said, Ashraf M.
Endoscopic findings in patients with inflammatory diarrhoea, a study of 40 cases.
Ann Pak Inst Med Sci Jan ;7(2):82-5.

Objective: To evaluate the frequency of various causes of inflammatory diarrhea in adult patients presenting to Teaching hospital. Study Design: A descriptive study. Place and duration: Department of Medicine lady`Readig hospital Peshawar, from July 2008 to January 2010. Inclusion Criteria: Subjects of both sexes from age fourteen and above having chronic inflammatory diarrhea. Exclusion Criteria: Subjects not consenting for inclusion in the study. Subjects already diagnosed to have chronic inflammatory diarrhea of any etiology. Materials and Methods: Forty subjects with features suggestive of chronic inflammatory diarrhea and consenting were included in the study. A comprehensive history was taken from all patients and a thorough physical examination was done on each subject. Baseline laboratory tests including full blood count, ESR, coagulation profile, liver function test and renal functions test were done on all patients. All patients underwent a digital rectal examination followed by sigmoidoscopy and biopsy. The information thus obtained was analyzed and frequencies were calculated for various findings. Results: Mean age of the study population was 40 with standard deviation of 6.32 Ulcerative colitis was the most common endoscopic diagnosis 45% followed by unremarkable mucosal findings in 32.5%. Colorectal mass lesion in 15%, radiation proctitis in 5%, Crohn’s disease and polyp adenoma in 2% each. Conclusion: Flexible sigmoidoscopy is simple, easier and helpful procedure in the diagnostic evaluation of patients presenting with features of inflammatory diarrhea. The common cause of chronic inflammatory diarrhea in our setup is ulcerative colitis followed by non specific colitis.

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