Mazhar Rafi, Zafar Iqbal, Muhammad Saleem, Muhammad Waseem, Jamal Anwar, Muhammad Saleem.
Pattern of congenital malformations and their neonatal outcome at Sheikh Zayed Medical College / Hospital Rahim Yar Khan.
Pak J Med Health Sci Jan ;5(1):94-6.

Objective: To highlight the pattern of congenital malformations in neonates admitted in a tertiary care Nursery and to evaluate their outcome after treatment. Study design: Descriptive study. Place & Duration of study: Department of Pediatrics Medicine & Surgery, Sheikh Zayed Medical College & Hospital, Rahim Yar Khan from January to December 2010. Methodology: A total of 4270 patients were admitted in nursery. Neonates with congenital malformations were diagnosed by clinical examination and by appropriate investigations. Surgical intervention was done accordingly. Results: Out of 4270 patients admitted in Nursery in one year, 645 patients (15%) were diagnosed as having congenital malformations. 335 were male and 302 were female & 8 were having ambiguous genitalia. 45 neonates died pre-operatively, 345 patients had surgery out of which 42 patients (12.1%) died in neonatal period, 217 were advised surgery after neonatal Period, and 38 patients refused surgery & were managed conservatively. Conclusion: By improvement in antenatal, postnatal diagnosis, urgent referral to tertiary care center, early surgical intervention and intensive post operative neonatal care, most infants can be saved.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com