Ghazi Aldehayat.
Lntraoperative dexmedetomidine administration at the end of surgery prevents post anesthetic shivering.
Rawal Med J Jan ;36(4):274-6.

Objective: To examine the efficacy of the alpha 2 agonist, Dexmedetomidine in prevention of postoperative shivering. Methods: Seventy ASA І-II patients were included in this randomized-prospective double blinded study. They were allocated into two groups to receive either Dexmedetomidine as a loading dose of 1 ug/ kg for 10 min or normal saline 20 minutes before the end of the surgery. Shivering and sedation were assessed postoperatively. Results: Demographic data were similar in both groups. Incidence of shivering was found to be significantly less in Dexmedetomidine group; 4 (12%) patients had some degree of shivering in comparisons to 16 (48%) in saline group (P<0.05). Sedation was significantly more in Dexmedetomidine group (P<0.05). Conclusion: Prophylactic low-dose Dexmedetomidine was found to be effective in preventing postoperative shivering.

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