Mohammed Shawagfeh, Ahmad S Sbaihat, Essa A Mayyas, Ala D Alomari, Safwan G Fawaris.
Low-dose bupivacaine with fentanyl spinal anesthesia to prevent spinal-induced hypotension in adults.
Rawal Med J Jan ;36(2):116-9.

Objectives: To assess the usefulness and efficacy of low-dose Bupivacaine with Fentanyl spinal anesthesia for prevention of hypotension while maintaining good anesthetic conditions. Patients and Methods: At Prince Rashid Hospital, 100 adult patients were randomized into two groups. The study group (F) comprised of 50 patients who received spinal anesthesia with Bupivacaine 7.5-9mg and fentanyl 25 μg, while in control group (B), 50 patients received Bupivacaine 12.5-15mg only. The homodynamic stability of the patients and the quality of the blocks were compared. Results: All patients had adequate duration of reliable blocks. More control group patients than study group patients required ephedrine due to hypotension. Conclusion: A reduced dose of Bupivacaine in combination with fentanyl provided reliable spinal anesthesia with few events of hypotension and little need for vasopressor support for blood pressure. (Rawal Med J 2011;36:116-119).

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