Muhamamd Babar Khan, Waseem Wali Muhammad, Khuram Haq Nawaz, Imran Ahmad, Muhammad Ali Yousaf.
Frequency of axonal variants of Guillain-barre syndrome in Pakistan.
Pak Armed Forces Med J Jan ;61(3):358-63.
Objective: To determine the frequency of axonal variants in our patients of Guillain-Barre Syndrome. Study Design: Descriptive study. Place and Duration: Department of Neurology, Military Hospital, Rawalpindi and Armed Forces Institute of Rehabilitation Medicine (AFIRM) from 01 Jan 2009 to 30 Jul 2010. Patients and Methods: Forty adult patients meeting the National Institute of Neurological Disorders and Stroke criteria for Guillain-Barre Syndrome (GBS) were consecutively enrolled in the study. Patient’s data, detailed history, examination and electrophysiological studies were carried out and recorded on a predesigned proforma. All patients were examined and reviewed by Consultant Physicians and Neurologists. Electromyography and Nerve conduction study testing was done by experienced electro-physiologists. Results: Axonal variants of Guillain-Barre Syndr ome constituted 16(40%) in our study. The variants of Guillian-Barre Syndrome were acute inflammatory polyradiculoneuropathy (AIDP) in 24(60%) patients followed by acute motor axonal neuropathy (AMAN) in 12(30%) and acute motor sensory axonal neuropathy (AMSAN) in 4(10%) patients. Conclusion: We report a high frequency of the axonal variants of Guillain-Barre Syndrome in Pakistan.
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