Ashfaq Ahmed Malik, Safdar Nawaz Malik, Muhammad Azeem Aslam.
Comparative efficacy of topical clotrimazole and 3% salicylic acid in otomycosis.
Rawal Med J Jan ;37(1):46-9.

Objective: To compare the efficacy of topical clotrimazole with 3 % salicylic acid in Otomycosis. Subjects and Method: One hundred patients were selected through non-probability convenience sampling technique. They were divided in two groups A and B with 50 patients in each. Group A was treated with clotrimazole and B with 3% Salicylic acid in affected ears three times a day for 2 weeks in the form of local drops. The outcome of both groups was compared by evaluating itching, blockade, otoscopic findings of fungal debris and ear discharge after two weeks of treatment. Results: Male to female ratio was 1.86 in both the groups. Their mean age was 36.65±19.27 years (range 6 to 93 years). Adults were 65.0% of all patients. Males experienced the more severe symptoms as compared to the females in both pre and post treatment phases (p > 0.050). 3% Salicylic Acid better controlled itching and ear blockade (p=0.000) as compared to clotrimazole Conclusion: Topical 3% Salicylic acid was better remedy in terms of alleviating symptoms of otomycosis. (RawalMed J 2012;37:46-49).

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