Ehsan Ullah, Raees Abbas Lail, Nergis Taj, Ijaz Alam.
Malignant and benign lesions of female genital tract - an experience at a tertiary care hospital in Bahawalpur - Pakistan.
Biomedica Jan ;28(2):149-52.

introduction: Frequencies and incidence rates of site – specific cancer and other pathological lesions are reported regularly in different studies, but mostly not by the histological type within site. This study reviews 3 years data of female genital tract tumours from 2008 – 2011, at Quaid-eAzam Medical College / Victoria Hospital, Bahawalpur. Methods: Data of the surgical specimens of uterus, ovary, vulva, vagina and cervix submitted to the Department of Pathology was reviewed and analysed for the type of specimen, tissue of origin, different diagnosed histological types and finally the behaviour of tumour i.e. benign or malignant. Results: A total of 1373 surgical specimens of female genital tract were submitted in 3 years, out of which 101 (7.4%) were malignant. Twenty nine percent and 28% of the neoplasms were from cervix and vagina respectively followed by vulva (17%), and then ovary and uterus (12% each). Squamous cell carcinoma was the most common invasive malignancy of the cervix (86%), vulva (77%), and vagina (71%). Adenocarcinoma was the most frequent malignancy in the uterus (53%) and ovary (61%). The 73% of the burden of benign disease was contributed by uterine lesions, 3/4th of them being leiomyoma and endometrial hyperplasia. Conclusions: Squamous cell carcinoma was the most frequent malignant tumour of the cervix, vagina and vulva. Adenocarcinoma was the most common malignancy in ovary and uterine corpus. Epidemiologic studies may provide more definite information by considering the effect of these subtypes in examining risk factors.

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