Saira Bashir, Ejaz Waris, Bilquis Asuleman, Ghulam Rasul Qureshi.
Frequency of different histopathological patterns of benign ovarian tumors in women with different age groups.
Pak J Med Health Sci Jan ;5(4):693-5.

Background: About 80% of benign ovarian tumors occur in older women between the age of 40 and 65 years. Benign tumor may be entirely asymptomatic and occasionally are unexpected findings on abdominal or pelvic examination or during surgery. Study design: We designed a non-interventional and descriptive study to find out the frequency of different histological patterns of benign ovarian tumors. Study also tried to relate the age and parity with the histopathological type benign ovarian tumor. Material and Methods: 25 consecutive ovarian tumor specimens were collected from Department of Histopathology, Sheikh Zayed Federal Postgraduate Medical Institute, Lahore. Duration of study was 3 months. The surgical specimens were fixed in 10% formalin solution. Multiple 3-5 mm sections were taken from the tumor with special emphasis on solid foci, area adjacent to ovarian surface and base of papillary formations. In addition sections were taken from the attached fallopian tube, ligaments and capsule of the tumurous ovary. In case of uterus, sections were also taken from the cervix, endometrium, myometrium, paracervix and parametrium. Results: 40-48% of benign tumors were observed in the age range of 21-60 years. While in the age range of 61-80 years the percentage of cases was decreased i.e. 8%. It was observed that in both nulliparous and multigravida (para >2) the number of benign tumors were more as compared to women who were unmarried or having primary gravida. Most common form of benign tumor was surface epithelial tumors (n=17) and germ cells tumors (n=4). Among surface epithelial tumors, 15 were serous cystademomas with a percent of 88.2 and 04 were mucinous cystadenomas with a percent of 23.5. On the other hand germ cell tumors were 04 mature cystic teratomas with 16%. Conclusion: The incidence of ovarian tumor is increasing gradually and there is need of awareness of disease in women. The incisional biopsy should be suggested where necessary for the histopathological typing of tumor. This is essential for early management and better prognosis.

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