Uzma Nabi, Nadia Naseem, Imrana Tanvir, Sabiha Riaz.
Clinicopathological pattern in 150 females presenting with benign and malignant ovarian tumors.
Pak J Med Health Sci Jan ;5(4):645-9.

Objective: To study the histological pattern of benign and malignant ovarian neoplasms. Study design: A cross- sectional study. Duration of study: Two and half years. Place of study: Departments of Pathology, Fatima Memorial Hospital and Arif laboratory, Hameed Latif Hospital Lahore. Methods: The study consisted of 150 specimens of ovarian tumors, received fixed in 10% formalin. Haematoxylin and Eosin stained slides were examined to determine the histological type by WHO classification. Results: Majority of these tumors were benign (74%), border line tumors were <2% and malignant tumors were 24.33%.Histologically the major categories were surface epithelial tumors 92 (61.33%), germ cell tumors 48 (32%) sex cord stromal tumors 9(6%) and metastatic adenocarcinoma 01 (0.66%).Amongst malignant tumors, the most common category was malignant surface epithelial tumor (67.56%) followed by malignant germ cell tumors (24.32%). Serous cystadenocarcinoma was the most common malignant ovarian tumor and 88% malignant surface tumors were seen in the 5th and 6th decades. All 9 malignant germ cell tumors (100%) occurred in patients below 30 years of age. Serous cystadenoma was most common benign tumor (38.73%) followed by mature cystic teratoma (35.13%). Benign ovarian tumors 60.36%( 67/111) were seen in 3rd and 4th decades. Conclusion: Epithelial tumors are the commonest variety of ovarian tumors followed by Germ cell tumors. There are minor differences from local and western studies.

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