Muhammad Farooq Hyder, Tariq Pervaiz Khan, Chaudhry Muhammad Tariq Munawar.
Incidence of Complications during Fluorescein Fundus Angiography (FFA) in Our Population.
Pak J Med Health Sci Jan ;6(2):320-2.

Objective: To see incidence of complications during FFA in our population. Method and material: A prospective descriptive study was conducted to document the incidence of adverse reactions with this procedure. Data collection was carried out between July 2007 and December 2008 at AFIO Rawalpindi. A total of 430 patients had undergone intravenous injection for retinal fluorescein angiography at Eye Department Rawalpindi. The sample ages were 40 to 65 years old. Patients with prior fluorescein angiography history, serious cardiovascular disease, bronchial asthma, pregnant patients or patients in use of corticosteroids, immunosuppressive, antihistamine drugs or receiving anticoagulants were excluded from the study. Results: The incidence of adverse reactions was 17.4%. Most adverse reactions were mild including urticaria/itching 50 patients (11.6%) and nausea/vomiting 20 patients (4.65%). Extravasation of dye was noted in 3 patients (0.69). Vasovagal attack with complete recovery without any intervention was noted in 2 patients (0.46%). No acute anaphylaxis reaction was noted. Conclusions: Fluorescein fundus angiography is a relatively safe diagnostic test. Adverse reactions do occur during or after FFA but majority of adverse reactions are mild in nature.

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