Tahir Rashid, Salman Baig, Imran Saeed, Zayed Mahasin.
Sinonasal Teratocarcinosarcoma: Management and Literature review.
Pak J Med Health Sci Jan ;6(3):794-6.

Teratocarcinosarcomas of sinonasal tract are very rare, histologically distinctive and highly malignant tumours containing both epithelial and mesenchymal elements. Around 66 cases have been reported in the world literature. Sinonasal teratocarcinosarcoma is predominantly found in males, most commonly affecting the nasal cavities and paranasal sinuses. The tumour’s aggressive and infiltrative behaviour leads to local recurrences and eventual treatment failure. The widely accepted treatment of choice for these tumours is surgery followed by radiotherapy. Due to the aggressive nature of the tumour, it has a tendency to recur and therefore a close follow-up following radical surgery and adjuvant radiotherapy is recommended. Chemotherapy has been used in recurrent and metastatic disease. However there is no convincing evidence that it increases the overall cure rate and survival. We report a case of a 32 years old male who was referred to our hospital with a diagnosis of sinonasal teratocarsinosarcoma of the left ethmoid following functional endoscopic sinus surgery for nasal polyposis. We carried out an anterior craniofacial resection of the tumour followed by radiotherapy.

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