Ahmad Hasan, Syed Husnain Bashir, Zeeshan Ghous.
Efficacy of Streptokinase on ST Segment Elevation MI in Diabetic and Non-Diabetic.
Pak J Med Health Sci Jan ;6(3):580-2.

Aims: To compare the efficacy of streptokinase on ST segment elevation MI in diabetic and non-diabetic Study design: It was a randomized clinical trial. Duration: From May 2012 to June 2012. Material and method: The patients of ST Segment Elevation Myocardial Infarction were recruited from the Department of Cardiology, Jinnah Hospital, Lahore. Result: Baseline characteristics of non-diabetic and diabetic myocardial infarction patients i.e. common age of the patients in both groups were similar and having no significant difference i.e. 49.43±4.27 in diabetic and 46.74±3.12 in non-diabetic group, 82.5% were male in diabetic and 72.5% in non-diabetic group. Comparison of efficacy of streptokinase on ST Segment elevation MI in diabetic and non-diabetic was recorded which shows 85% in non-diabetic and only 30% in diabetic patients. P value was calculated as 0.00. Conclusion: In light of the present results we may conclude that the thrombolytic therapy is more effective in non-diabetics than diabetic subjects with STEMI, however, more attention should be given to the diabetic individuals before administration of thrombolytic therapy

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